Scaling in biology

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Scaling in biology

Ernest Rutherford is credited with the provocative assertion that all attempts to expand human knowledge are either physics or stamp collecting. Whatever your opinion of this statement, the two modes are not mutually exclusive, and some of the most interesting efforts to marry the two endeavours have looked at questions of scale in biology. Evolution may drive species to different sizes, shapes...

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Allometric Scaling in Biology

The design of living beings is not only a matter of molecular biology but also of geometry and physics. This was once more demonstrated with a biophysical model by G. B. West et al. (1) that had been fine-tuned to predict the famous scaling law of metabolism (2), namely a 3/4 power relation between body mass and energy consumption. While properties and predictions of the model are remarkable, a...

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Allometric Scaling in Biology

The design of living beings is not only a matter of molecular biology but also of geometry and physics. This was once more demonstrated with a biophysical model by G. B. West et al. (1) that had been fine-tuned to predict the famous scaling law of metabolism (2), namely a 3/4 power relation between body mass and energy consumption. While properties and predictions of the model are remarkable, a...

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Cell Biology: Scaling and the Emergence of Evolutionary Cell Biology

A new study investigating the origins of diversity in the structure of the mitotic spindle in nematode embryos, at timescales spanning a few generations to hundreds of millions of years, finds that most features of the spindle evolve via a scaling relationship generated by natural selection acting directly upon embryo size.

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Evaluating scaling models in biology using hierarchical Bayesian approaches

Theoretical models for allometric relationships between organismal form and function are typically tested by comparing a single predicted relationship with empirical data. Several prominent models, however, predict more than one allometric relationship, and comparisons among alternative models have not taken this into account. Here we evaluate several different scaling models of plant morpholog...

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ژورنال

عنوان ژورنال: Current Biology

سال: 2009

ISSN: 0960-9822

DOI: 10.1016/j.cub.2008.10.042